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HENAN SUNLAKE ENTERPRISE CORPORATION

Country: China (Mainland)

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127191-97-3 C38H35N5O6S2 KN-62

CAS NO.127191-97-3

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,
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Product Details

Keywords

  • ISOQUINOLINYLSULFONYL
  • METHYLAMINO
  • phenylisoquinolinesulfonicacid

Quick Details

  • ProName: 127191-97-3 C38H35N5O6S2 KN-62
  • CasNo: 127191-97-3
  • Molecular Formula: C38H35N5O6S2
  • Appearance: Yellow Solid
  • Application: 127191-97-3 ...
  • DeliveryTime: 7-10 days after payment
  • PackAge: As required
  • Port: Shanghai/Tianjin/Qingdao
  • ProductionCapacity: 100-200 Kilogram/Month
  • Purity: 99%
  • Storage: ?20°C
  • Transportation: By air/sea/express
  • LimitNum: 1 Kilogram
  • Grade: Pharma Grade

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About Certificate

 

1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)

 

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1. Quality control, before shipment, free sample for test.
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About Company

 
HenNan sunlake enterprise corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
     Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs ,  Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East ,  Africa , South America and some other countries and areas.
    We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you  better with our high - quality products and professional team.
    We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.
     We  welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!

Details

Product Name: KN-62
Synonyms: KN-62;4-[(2S)-2-[(5-ISOQUINOLINYLSULFONYL)METHYLAMINO]-3-OXO-3-(4-PHENYL-1-PIPERAZINYL)PROPYL] PHENYL ISOQUINOLINESULFONIC ACID ESTER;1-[N,O-BIS-(5-ISOQUINOLINESULFONYL)-N-METHYL-L-TYROSYL]-4-PHENYLPIPERAZINE;(S)-5-ISOQUINOLINESULFONIC ACID 4-(2-[(5-ISOQUINOLINYLSULFONYL)METHYLAMINO]- 3-OXO-3-[4-PHENYL-1-PIPERAZINYL]PROPYL)PHENYL ESTER;1-(N,O-BIS-(5-ISOQUINOLINESULFONYL)-*N-M ETHYL-L-TYR;KN-62 97%;KN-62, 99+%;4-((2S)-2-((5-isoquinolinylsulfonyl)methylamino)-3-oxo-3-(4-phenyl-1-piperazinyl)propyl)phenylisoquinolinesulfonicacid
CAS: 127191-97-3
MF: C38H35N5O6S2
MW: 721.84
EINECS:  
Product Categories: Protein Kinase Inhibitors and Activators;Protein Kinase;Inhibitor
Mol File: 127191-97-3.mol
KN-62 Structure
 
KN-62 Chemical Properties
mp  92-94°C
density  1.388
storage temp.  −20°C
solubility  45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.93 mg/mL
form  solid
color  white
CAS DataBase Reference 127191-97-3(CAS DataBase Reference)
 
Safety Information
Safety Statements  24/25
WGK Germany  3
MSDS Information
Provider Language
ACROS English
SigmaAldrich English
 
KN-62 Usage And Synthesis
Chemical Properties Yellow Solid
Usage A specific inhibitor of Ca2+/Calmodulin-dependent protein kinase II
Usage selectively inhibits rat brain Ca2+/cadmodulin-dependent protein kinase II,
Biological Activity Selective, cell-permeable inhibitor of CaM kinase II (IC 50 = 0.9 μ M). Binds directly to the calmodulin binding site of the enzyme. Potent non-competitive antagonist at the P2X 7 receptor (IC 50 = 15 nM). Also available as part of the Mixed Kinase Inhibitor Tocriset™ .
 
KN-62 Preparation Products And Raw materials

 

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