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CAS NO.1126-09-6
| Ethyl 4-piperidinecarboxylate Basic information |
| Product Name: | Ethyl 4-piperidinecarboxylate |
| Synonyms: | 4-Carbethoxypiperidine;ISONIPECOTINIC ACID ETHYL ESTER;ISONIPECOTIC ACID ETHYL ESTER;ETHYL ISONIPECOTATE;ETHYL PIPERIDINE-4-CARBOXYLATE;ETHYL 4-PIPERIDINECARBOXYLATE;LABOTEST-BB LT00159543;4-PIPERDINECARBOXYLIC ACID, ETHYL ESTER |
| CAS: | 1126-09-6 |
| MF: | C8H15NO2 |
| MW: | 157.21 |
| EINECS: | 214-416-7 |
| Product Categories: | Pharmaceutical Intermediates;Piperidines, Piperidones, Piperazines;pharmacetical;AMINOACIDS DERIVATIVES;Piperidine;Building Blocks;C8;Chemical Synthesis;Heterocyclic Building Blocks;Piperidines;Heterocycles |
| Mol File: | 1126-09-6.mol |
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| Ethyl 4-piperidinecarboxylate Chemical Properties |
| bp | 204 °C(lit.) |
| density | 1.02 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Fp | 176 °F |
| Water Solubility | miscible |
| BRN | 118419 |
| CAS DataBase Reference | 1126-09-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethyl piperidine-4-carboxylate(1126-09-6) |
| Safety Information |
| Hazard Codes | C,Xi |
| Risk Statements | 34-36/37/38 |
| Safety Statements | 23-24/25-36-26 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| HS Code | 29333999 |
| MSDS Information |
| Provider | Language |
|---|---|
| Ethyl 4-piperidinecarboxylate | English |
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| Ethyl 4-piperidinecarboxylate Usage And Synthesis |
| Chemical Properties | clear colorless to slightly brown liquid |
| Usage | Reactant for synthesis of:• ;SMN protein modulators1• ;β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition2• ;Nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone3• ;RhoA inhibitors for cardiovascular disease therapy4• ;Saccharin derived Mannich bases as antimicrobials and antioxidants5Reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates6 |
| Usage | Reactant for synthesis of SMN protein modulators and β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition. |
| Ethyl 4-piperidinecarboxylate Preparation Products And Raw materials |
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