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HENAN SUNLAKE ENTERPRISE CORPORATION

Country: China (Mainland)

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109581-93-3 C44H69NO12 TACROLIMUS

CAS NO.109581-93-3

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,
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Product Details

Keywords

  • 18-tetramethyl
  • 3-methoxycyclohexyl
  • tacrolimushydrate

Quick Details

  • ProName: 109581-93-3 C44H69NO12 TACROLIMUS
  • CasNo: 109581-93-3
  • Molecular Formula: C44H69NO12
  • Appearance: As detailed
  • Application: 109581-93-3 ...
  • DeliveryTime: 7-10 days after payment
  • PackAge: As required
  • Port: Shanghai/Tianjin/Qingdao
  • ProductionCapacity: 100-200 Kilogram/Month
  • Purity: 99%
  • Storage: Store at -20°C
  • Transportation: By air/sea/express
  • LimitNum: 1 Kilogram
  • Grade: Pharma Grade

Superiority

About Certificate

 

1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)

 

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1. Quality control, before shipment, free sample for test.
2. Prompt shipment with professional documents
3. Packing as your request, with photo before shipment
4. Mixed containers with different mixed items in one container

 

About Company

 
HenNan sunlake enterprise corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
     Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs ,  Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East ,  Africa , South America and some other countries and areas.
    We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you  better with our high - quality products and professional team.
    We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.
     We  welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!

Details

Product Name: TACROLIMUS
Synonyms: FK-506;,8s*,9e,12r*,14r*,15s*,16r*,18s*,19s*,26ar*))-;18-tetramethyl-8-(2-propenyl)-,monohydrate,(3s-(3r*(e(1s*,3s*,4s*)),4s*,5r*;3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-9,10,12,;tacrolimushydrate;tsukubaenolidehydrate;FK-506 MONOHYDRATE;Tacarolimus
CAS: 109581-93-3
MF: C44H69NO12
MW: 822.04
EINECS:  
Product Categories: Signalling
Mol File: 109581-93-3.mol
TACROLIMUS Structure
 
TACROLIMUS Chemical Properties
storage temp.  −20°C
 
Safety Information
Hazard Codes  T
Risk Statements  25
Safety Statements  45
RIDADR  UN 2811 6.1/PG 3
RTECS  KD4201200
MSDS Information
 
 
TACROLIMUS Usage And Synthesis
Usage immune suppressant, antifungal
Biological Activity Potent calcineurin (protein phosphatase 2B) inhibitor that requires FK 506-binding protein 12 (FKBP12) for activity (IC 50 = 3 nM). Inhibits secretion of IL-1, IL-2 (IC 50 = 1 nM), IL-3, IL-4, IL-6 (IC 50 = 35 nM), GM-CSF, TNF α (IC 50 = 10 nM), IFN γ and Myc from activated T-cells in vitro . Exhibits potent immunosuppressive, neuroprotective and anticonvulsant activity in vivo .
 
TACROLIMUS Preparation Products And Raw materials

 

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