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HENAN SUNLAKE ENTERPRISE CORPORATION

Country: China (Mainland)

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107007-99-8 C18H25ClN4O Granisetron hydrochloride

CAS NO.107007-99-8

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,
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Product Details

Keywords

  • endo-monohydrochlorid
  • KYTRIL
  • 1h-indazole-3-carboxamid

Quick Details

  • ProName: 107007-99-8 C18H25ClN4O Granisetron ...
  • CasNo: 107007-99-8
  • Molecular Formula: C18H25ClN4O
  • Appearance: White to Off-White Crystalline Sold
  • Application: 107007-99-8 ...
  • DeliveryTime: 7-10 days after payment
  • PackAge: As required
  • Port: Shanghai/Tianjin/Qingdao
  • ProductionCapacity: 100-200 Kilogram/Month
  • Purity: 99%
  • Storage: room temperature
  • Transportation: By air/sea/express
  • LimitNum: 1 Kilogram
  • Grade: Pharma Grade

Superiority

About Certificate

 

1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)

 

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1. Quality control, before shipment, free sample for test.
2. Prompt shipment with professional documents
3. Packing as your request, with photo before shipment
4. Mixed containers with different mixed items in one container

 

About Company

 
HenNan sunlake enterprise corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
     Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs ,  Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East ,  Africa , South America and some other countries and areas.
    We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you  better with our high - quality products and professional team.
    We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.
     We  welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!

Details

Product Name: Granisetron hydrochloride
Synonyms: 1-methyl-n-(9-methyl-9-azabicyclo(3.3.1)non-3-yl)-1h-indazole-3-carboxamid;endo-1-methyl-n-(9-methyl-9-azabicyclo(3.3.1)non-3-yl)-1h-indazole-3-carboxa;endo-monohydrochlorid;midehydrochloride;1-METHYL-N-[(3-ENDO)-9-METHYL-9-AZABICYCLO[3.3.1]NON-3-YL]-1H-INDAZOLE-3-CARBOXAMIDE HYDROCHLORIDE;KYTRIL;BRL-43694A;GRANISERTROL HYDROCHLORIDE
CAS: 107007-99-8
MF: C18H25ClN4O
MW: 348.87
EINECS:  
Product Categories: Pharmaceutical material and intermeidates;Active Pharmaceutical Ingredients;API;Heterocyclic Compounds;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals;Granisetron;Serotonin receptor;Serotonin;Heterocycles;SINTROM;Other APIs;Digestive System
Mol File: 107007-99-8.mol
Granisetron hydrochloride Structure
 
Granisetron hydrochloride Chemical Properties
mp  290-292°C
storage temp.  Room temp
CAS DataBase Reference 107007-99-8(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xn,Xi
Risk Statements  22-62-37/38-36/37/38-36
Safety Statements  26-36-37
RTECS  NK7882200
Chemical Properties It is white or yellowish white crystalline powder and is odorless. It is easily soluble in water but hardly soluble in methanol, extremely hardly to be dissolved in ethanol and almost insoluble in ether. It has a melting point of 290-292 ℃. For acute toxicity LD50, female mice, male and female rats (mg / kg): 17, 25, 14, 16, respectively. Intravenous injection.
Application It is the selective antagonist of the 5-serotonin 3 (5-HT3) in peripheral and central nervous system.
Chemical Properties White to Off-White Crystalline Sold
Usage anticoagulant
Usage A specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemothera py. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarini c receptor
Biological Activity 5-HT 3 receptor antagonist that possesses potent antiemetic activity.
 
Granisetron hydrochloride Preparation Products And Raw materials
Raw materials Hydrochloric acid-->Granisetron

 

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