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103577-45-3 C16H14F3N3O2S Lansoprazole

CAS NO.103577-45-3

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Keywords

  • 103577-45-3 C16H14F3N3O2S Lansoprazole
  • 103577-45-3
  • C16H14F3N3O2S

Quick Details

  • ProName: 103577-45-3 C16H14F3N3O2S ...
  • CasNo: 103577-45-3
  • Molecular Formula: C16H14F3N3O2S
  • Appearance: white powder
  • Application: For the treatment of acid-reflux disor...
  • DeliveryTime: 5-7 days after payment
  • PackAge: Woven bag
  • Port: Tianjin Shanghai
  • ProductionCapacity: 1 Kilogram/Day
  • Purity: 99%
  • Storage: Normal temperature
  • Transportation: Ocean shipping Express delivery
  • LimitNum: 10 Gram

Superiority

Lansoprazole Basic information
Product Name: Lansoprazole
Synonyms: 1h-benzimidazole,2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)su;2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1h-benz;lfinyl)-;PREVACID;OGAST;LANSOPRAZOLE;LANSAPRAZOLE;LANSOX
CAS: 103577-45-3
MF: C16H14F3N3O2S
MW: 369.36
EINECS:  
Product Categories: Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Ion Pump Inhibitors;Monovalent Ion Channels;Voltage-gated Ion Channels;ATPase;Pharmaceutical Intermediates;API Reference StandardFree Base API;Other APIs;pharmaceutical
Mol File: 103577-45-3.mol
Lansoprazole Structure
 
Lansoprazole Chemical Properties
mp  178-182°C dec.
storage temp.  2-8°C
form  powder
color  off-white
CAS DataBase Reference 103577-45-3(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  2
RTECS  DD9487500
Hazardous Substances Data 103577-45-3(Hazardous Substances Data)
 
Lansoprazole Usage And Synthesis
Chemical Properties White Crystalline Powder
Usage Used as a gastric proton pump inhibitor. An antiulcerative
Usage anthelmintic
Usage A H+,K+-ATPase inhibitor that displays antisecretory activity
Usage Treatment of gastroesophageal reflux disease (GERD), erosive esophagitis, duodenal ulcers, Helicobacter pylori (H. pylori) infections,stomach ulcers, prevention of stomach ulcers in those people taking non-steroidal anti-inflammatory drugs (NSAIDs), such
Usage For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevention of gastroinetestinal bleeds with NSAID use.
Biological Activity H + ,K + -ATPase inhibitor (IC 50 = 6.3 μ M) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC 50 = 0.09 μ M for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacterial against Helicobacter pylori in vitro . Also blocks swelling-dependent chloride channel (ICIswell) in NIH3T3 fibroblasts. More potent than omeprazole (5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole ).
 
Lansoprazole Preparation Products And Raw materials
Raw materials Acetic acid glacial-->Thionyl chloride-->Acetic anhydride-->tert-Butanol-->Vanadium pentoxide -->2,3-Lutidine-->2-Mercaptobenzimidazole

 

Details

Lansoprazole Basic information
Product Name: Lansoprazole
Synonyms: 1h-benzimidazole,2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)su;2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1h-benz;lfinyl)-;PREVACID;OGAST;LANSOPRAZOLE;LANSAPRAZOLE;LANSOX
CAS: 103577-45-3
MF: C16H14F3N3O2S
MW: 369.36
EINECS:  
Product Categories: Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Ion Pump Inhibitors;Monovalent Ion Channels;Voltage-gated Ion Channels;ATPase;Pharmaceutical Intermediates;API Reference StandardFree Base API;Other APIs;pharmaceutical
Mol File: 103577-45-3.mol
Lansoprazole Structure
 
Lansoprazole Chemical Properties
mp  178-182°C dec.
storage temp.  2-8°C
form  powder
color  off-white
CAS DataBase Reference 103577-45-3(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  2
RTECS  DD9487500
Hazardous Substances Data 103577-45-3(Hazardous Substances Data)
 
Lansoprazole Usage And Synthesis
Chemical Properties White Crystalline Powder
Usage Used as a gastric proton pump inhibitor. An antiulcerative
Usage anthelmintic
Usage A H+,K+-ATPase inhibitor that displays antisecretory activity
Usage Treatment of gastroesophageal reflux disease (GERD), erosive esophagitis, duodenal ulcers, Helicobacter pylori (H. pylori) infections,stomach ulcers, prevention of stomach ulcers in those people taking non-steroidal anti-inflammatory drugs (NSAIDs), such
Usage For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevention of gastroinetestinal bleeds with NSAID use.
Biological Activity H + ,K + -ATPase inhibitor (IC 50 = 6.3 μ M) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC 50 = 0.09 μ M for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacterial against Helicobacter pylori in vitro . Also blocks swelling-dependent chloride channel (ICIswell) in NIH3T3 fibroblasts. More potent than omeprazole (5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole ).
 
Lansoprazole Preparation Products And Raw materials
Raw materials Acetic acid glacial-->Thionyl chloride-->Acetic anhydride-->tert-Butanol-->Vanadium pentoxide -->2,3-Lutidine-->2-Mercaptobenzimidazole
  HenNan sunlake enterprise corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material . 
   Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas. 
    We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you better with our high - quality products and professional team. 
     We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market. We welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!
 
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