Product Certification&
Enterprise Certification
Country: China (Mainland)
Business Type:Trading Company
Tel: +86-371- 86259723
Tel: 17734809689
Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
Mobile: 17734809689
Tel: +86-371- 86259723
Fax: +86-371- 86259723
Province/state: HENAN
City: ZHENGZHOU
Street: Mingmen International Center, NO.222 Dongming Road,Zhengzhou,Henan,China
MaxCard:
CAS NO.94497-51-5
Tamibarotene Basic information |
Product Name: | Tamibarotene |
Synonyms: | AM80;Tamibarotene;4-[(5,5,8,8-Tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic acid;4-[[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)amino]carbonyl]benzoic Acid;Am 80 (pharmaceutical);Amnolake;NSC 608000;Retinoid AM 80 |
CAS: | 94497-51-5 |
MF: | C22H25NO3 |
MW: | 351.44 |
EINECS: | |
Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Retinoids;Inhibitors |
Mol File: | 94497-51-5.mol |
Tamibarotene Chemical Properties |
mp | 231-232°C |
storage temp. | Store at RT |
Safety Information |
Tamibarotene Usage And Synthesis |
Chemical Properties | Crystalline Solid |
Usage | Synthetic retinoic acid receptor-a/ selective retinoid. Antineoplastic |
Usage | Synthetic retinoic acid receptor-α/β-selective retinoid. Antineoplastic. |
Biological Activity | Retinoic acid receptor α (RAR α ) agonist that induces differentiation (ED 50 = 0.79 nM) and apoptosis of HL-60 cells in vitro . Exhibits antiproliferative effects against a variety of human tumor cells lines (mean values of 35, 40 and 60% growth inhibition at 0.1, 1 and 10 μ M respectively) and displays anticancer activity against acute promyelocytic leukemia in vivo . |
Tamibarotene Preparation Products And Raw materials |
Tamibarotene Basic information |
Product Name: | Tamibarotene |
Synonyms: | AM80;Tamibarotene;4-[(5,5,8,8-Tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic acid;4-[[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)amino]carbonyl]benzoic Acid;Am 80 (pharmaceutical);Amnolake;NSC 608000;Retinoid AM 80 |
CAS: | 94497-51-5 |
MF: | C22H25NO3 |
MW: | 351.44 |
EINECS: | |
Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Retinoids;Inhibitors |
Mol File: | 94497-51-5.mol |
Tamibarotene Chemical Properties |
mp | 231-232°C |
storage temp. | Store at RT |
Safety Information |
Tamibarotene Usage And Synthesis |
Chemical Properties | Crystalline Solid |
Usage | Synthetic retinoic acid receptor-a/ selective retinoid. Antineoplastic |
Usage | Synthetic retinoic acid receptor-α/β-selective retinoid. Antineoplastic. |
Biological Activity | Retinoic acid receptor α (RAR α ) agonist that induces differentiation (ED 50 = 0.79 nM) and apoptosis of HL-60 cells in vitro . Exhibits antiproliferative effects against a variety of human tumor cells lines (mean values of 35, 40 and 60% growth inhibition at 0.1, 1 and 10 μ M respectively) and displays anticancer activity against acute promyelocytic leukemia in vivo . |
Tamibarotene Preparation Products And Raw materials |