Keywords

• 703-95-7
• 703-95-7
• 703-95-7

Quick Details

• ProName: 703-95-7
• CasNo: 703-95-7
• Molecular Formula: C5H3FN2O4
• Appearance: clear colorless liquid
• Application: 703-95-7
• DeliveryTime: Promopt .
• PackAge: 1g;5g;10g;25g;50g;100g;500g;1KG;5KG,25...
• Port: China main ports
• ProductionCapacity: 100 Kilogram/Month
• Purity: 98% purity
• Storage: 2-8, cold storage, to avoid light stor...
• Transportation: by air /by sea /by courier
• LimitNum: 1 Kilogram
• Grade: Industrial Grade,Pharma Grade,Electron...
• Valid Period: 6 month
• Application: Multipurpose intermediate
• Certification: ISO/9001 Certificate

Superiority

1. ISO 9001 approved, GMP producing standard,Proffesional QA system, our quality is guaranteed.

2. Facotory direct sale, most comptive price ensured;

3. Audited Supplier on lookchem, No trick, No Scam!

4. Enough stock can make sure safe delivery.

5. Complete before and after sale service, welcome your questions and glad to help.

HenNan sunlake enterprise corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material . 
Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas. 

Details

5-Fluoroorotic acid Basic information

Product Name:	5-Fluoroorotic acid
Synonyms:	1,2,3,6-tetrahydro-2,6-dioxo-5-fluoro-4-pyrimidinecarboxylicaci;1,2,3,6-tetrahydro-2,6-dioxo-5-fluoro-4-pyrimidinecarboxylicacid;5-fluoro-1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylicaci;5-fluoroorotate;5-fluoro-oroticaci;ent-26398;fluorooroticacid;fo
CAS:	703-95-7
MF:	C5H3FN2O4
MW:	174.09
EINECS:	211-876-0
Product Categories:	Aromatic Halides (substituted);Nucleotides and Nucleosides;Biochemistry;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents;5-FOA;Bases & Related Reagents;Nucleotides;pyrimidine;Fluorine series
Mol File:	703-95-7.mol

5-Fluoroorotic acid Chemical Properties

mp	278 °C (dec.)(lit.)
storage temp.	−20°C
solubility	NH4OH 4 M: 50 mg/mL, clear, faintly yellow
Merck	4176
CAS DataBase Reference	703-95-7(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	22-36/37/38
Safety Statements	26-36-36/37/39-27
WGK Germany	3
RTECS	UV7800000
F	10
Hazard Note	Irritant
HazardClass	IRRITANT

MSDS Information

Provider	Language
2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid	English

5-Fluoroorotic acid Usage And Synthesis

Chemical Properties

White to Off-White Crystalline Solid

Usage

5-FOA has become a valuable tool for research in the field of molecular genetics. It has been employed in the selection of resistant strains of Saccharomyces cerevisiae that possess a mutant URA3 gene which renders them orotidine-5'-phosphate decarboxylase deficient. 5-FOA is coverted to 5-fluorouridine monophosphate (5-FUMP) in yeast cells, which can become incorporated into RNA or metabolized to the highly toxic 5-fluoro-2’-deoxyuridine monophosphate (5-FdUMP). 5-FdUMP is a potent inhibitor of thymidylate synthase (TS), causing the cessation of DNA synthesis. More recently, 5-FOA has been shown to possess potent antimalarial activity against both chloroquine-susceptible and chloroquine-resistant clones of Plasmodium falciparum. Studies indicate that TS is the primary target of 5-FOA in malarial parasites. The combination of 5-FOA and uracil has been effective in treating mice infected with Plasmodium yoelli. 5-FOA may also have potential in the treatment of human malarial infections when used in combination with other agents.

HenNan sunlake enterprise corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material . 
Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas.