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CAS NO.67227-56-9
| Fenoldopam Basic information |
| Product Name: | Fenoldopam |
| Synonyms: | (r)-6-chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1h-3-benzazepine-7,8-diol;6-CHLORO-2,3,4,5-TETRAHYDRO-1-(4-HYDROXYPHENYL)-1H-3-BENZAZEPINE-7,8-DIOL HYDROCHLORIDE;6-CHLORO-2,3,4,5-TETRAHYDRO-1-(4-HYDROXYPHENYL)-1H-3-BENZAZEPINE-7,8-DIOL MESYLATE;CORLOPAM MESYLATE;FENOLDOPAM;FENOLDOPAM HYDROCHLORIDE;FenoldopamMesylateBase;6-Chloro-2，3，4，5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benz．A~pine-7，8-diol |
| CAS: | 67227-56-9 |
| MF: | C16H16ClNO3 |
| MW: | 305.76 |
| EINECS: | 266-612-7 |
| Product Categories: | Agonists;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals;API |
| Mol File: | 67227-56-9.mol |
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| Fenoldopam Chemical Properties |
| storage temp. | 2-8°C |
| solubility | DMSO: >12 mg/mL |
| color | off-white |
| CAS DataBase Reference | 67227-56-9(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 22-36-42/43 |
| Safety Statements | 22-26-36/37/39 |
| WGK Germany | 3 |
| Fenoldopam Usage And Synthesis |
| Usage | Dopamine D1-receptor agonist. Antihypertensive. |
| Usage | dopamine receptor agonists |
| Biological Activity | Selective D 1 -like dopamine receptor partial agonist (EC 50 = 57 nM). Vasodilator in vivo and does not readily cross the blood-brain barrier. Also α 2 -adrenoceptor antagonist in vitro (K i = 15-25 nM). |
| Fenoldopam Preparation Products And Raw materials |
| Raw materials | Nitromethane-->Veratraldehyde-->Isovanillin-->3,4-Dimethoxyphenethylamine |
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