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CAS NO.65-86-1
| Orotic acid Basic information |
| Product Name: | Orotic acid |
| Synonyms: | 1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidecarboxylicacid[qr];1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylicaci;2,6-Dihydroxy-4-pyrimidinecarboxylic acid;4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-;4-pyrimidinecarboxylicacid,1,2,3,6-tetrahydro-2,6-dioxo-[qr];6-carboxyuracil[qr];acideorotique(french)[qr];acidoorotico[qr] |
| CAS: | 65-86-1 |
| MF: | C5H4N2O4 |
| MW: | 156.1 |
| EINECS: | 200-619-8 |
| Product Categories: | Vitamin Ingredients;Daily-use cosmetics and medicine nucleic acid biological research;Inhibitors |
| Mol File: | 65-86-1.mol |
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| Orotic acid Chemical Properties |
| mp | >300°C |
| Water Solubility | Slightly soluble |
| Merck | 13,6942 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 65-86-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Orotic acid(65-86-1) |
| EPA Substance Registry System | 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo- (65-86-1) |
| Safety Information |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36/37/39-22-37/39 |
| WGK Germany | 3 |
| RTECS | RM3180000 |
| F | 10-21 |
| Hazard Note | Harmful |
| Hazardous Substances Data | 65-86-1(Hazardous Substances Data) |
| Orotic acid Usage And Synthesis |
| Chemical Properties | white crystalline powder |
| Usage | hepatoprotectant, uricosuric agent |
| General Description | White crystals or crystalline powder. |
| Air & Water Reactions | Slightly soluble in water. |
| Reactivity Profile | Carboxylic acids, such as Orotic acid, donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water. Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions. The pH of solutions of carboxylic acids is therefore less than 7.0. Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry. Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in Orotic acid to corrode or dissolve iron, steel, and aluminum parts and containers. Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide. The reaction is slower for dry, solid carboxylic acids. Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide. Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat. Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat. A wide variety of products is possible. Like other acids, carboxylic acids may initiate polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions. |
| Fire Hazard | Flash point data for Orotic acid are not available; however, Orotic acid is probably combustible. |
| Orotic acid Preparation Products And Raw materials |
English name:Orotic acid
CAS No.:65-86-1
Molecular formula:C5H4N2O4
Molecular weight: 156.1
Appearance:White crystal powder
Melting point:>300°C
Use:Vitamin drugs. Mainly used for daily cosmetics and pharmaceuticals, nucleic acids, biological research, medicine for the system jaundice liver medicine, heart disease drugs for hyperuricemia, hypercholesterolemia, chronic hepatitis, cirrhosis. Can also be used as anti-anemia and nutritional
Structure formula:
