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CAS NO.64-75-5
Tetracycline hydrochloride Basic information |
Tetracycline hydrochloride Chemical Properties |
mp | 220-223 °C(lit.) |
alpha | -252 º (c=0.5, H2O) |
refractive index | -253 ° (C=0.5, 0.1mol/L HCl) |
storage temp. | 2-8°C |
solubility | H2O: 10 mg/mL as a stock solution. Stock solutions should be filtered sterilized and stored at −20°C. Stable at 37°C for 4 days. |
form | powder |
Water Solubility | 50 g/L |
Merck | 14,9196 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 64-75-5(CAS DataBase Reference) |
EPA Substance Registry System | 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5, 5a,6,11,12a-octahydro-3,6, 10,12,12a-pentahydroxy-6- methyl-1,11-dioxo-, monohydrochloride, (4S,4aS,5aS,6S,12aS)-(64-75-5) |
Safety Information |
Hazard Codes | Xi,Xn |
Risk Statements | 36/37/38-20/21/22 |
Safety Statements | 26-36 |
WGK Germany | 2 |
RTECS | QI9100000 |
F | 8-10-23 |
HS Code | 29413000 |
MSDS Information |
Provider | Language |
---|---|
[4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha)]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide hydrochloride | English |
ACROS | English |
SigmaAldrich | English |
ALFA | English |
Tetracycline hydrochloride Usage And Synthesis |
Chemical Properties | Yellow crystalline powder |
Usage | Antibiotic substance produced by Streptomyces spp. Antiamebic; antibacterial; antirickettsial. |
Usage | antibacterial, antiamebic, antirickettsial |
Usage | Tetracycline hydrochloride is a salt prepared from tetracycline taking advantage of the basic dimethylamino group which protonates and readily forms the salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Tetracycline hydrochloride has broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-unit,s blocking protein synthesis. |
Usage | cell nuclei stain |
General Description | Crystals or fine bright yellow powder. pH of 2% aqueous solution: 2.1 - 2.3. |
Air & Water Reactions | Water soluble. |
Reactivity Profile | Tetracycline hydrochloride is acidic. Reacts with strong oxidizing agents . |
Fire Hazard | Flash point data concerning Tetracycline hydrochloride are not available, however, Tetracycline hydrochloride is probably combustible. |
Tetracycline hydrochloride Preparation Products And Raw materials |