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CAS NO.6066-82-6
N-Hydroxysuccinimide Basic information |
Product Name: | N-Hydroxysuccinimide |
Synonyms: | N-HYDROXY-2,5-PYRROLIDINEDIONE;NHS;N-HYDROXYSUCCINIMDE;N-HYDROXYSUCCINIMIDE;N-HYDROXYSUCCINIMIDE POLYMER-BOUND;1-hydroxy-5-pyrrolidinedione;1-Hydroxysuccinimide;5-Pyrrolidinedione,1-hydroxy-2 |
CAS: | 6066-82-6 |
MF: | C4H5NO3 |
MW: | 115.09 |
EINECS: | 228-001-3 |
Product Categories: | Peptide coupling agents;Medical Intermediates;Heterocycles;Other Reagents;Miscellaneous Reagents;Biochemistry;Condensation & Active Esterification;Coupling Reactions (Peptide Synthesis);N-Substituted Maleimides, Succinimides & Phthalimides;N-Substituted Succinimides;Peptide Synthesis;Synthetic Organic Chemistry;Coupling ReagentsSynthetic Reagents;Coupling;Others;Supported Reagents;Supported Synthesis;APIS;Zero-Length Crosslinker;heteroXlink |
Mol File: | 6066-82-6.mol |
N-Hydroxysuccinimide Chemical Properties |
mp | 95-98 °C(lit.) |
storage temp. | 2-8°C |
Water Solubility | SOLUBLE |
Sensitive | Hygroscopic |
BRN | 113913 |
Stability: | Stable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides, strong bases. Protect from moisture. |
CAS DataBase Reference | 6066-82-6(CAS DataBase Reference) |
NIST Chemistry Reference | N-hydroxylsuccinimide(6066-82-6) |
EPA Substance Registry System | 2,5-Pyrrolidinedione, 1-hydroxy-(6066-82-6) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 22-24/25-26-36 |
WGK Germany | 3 |
Hazard Note | Irritant |
HS Code | 29251995 |
MSDS Information |
Provider | Language |
---|---|
1-Hydroxy-2,5-pyrrolidinedione | English |
SigmaAldrich | English |
ACROS | English |
ALFA | English |
N-Hydroxysuccinimide Usage And Synthesis |
Chemical Properties | White to pale yellow |
Usage | Additive used in the carbodiimide method for improved amidations and peptide couplings. |
N-Hydroxysuccinimide Preparation Products And Raw materials |
Raw materials | Hydroxylamine hydrochloride-->Succinic anhydride |
Preparation Products | Enalapril-->Imidapril-->N-ACRYLOXYSUCCINIMIDE-->Arbekacin-->Aspoxicillin-->GUSPERIMUS |
N-Hydroxysuccinimide Basic information |
Product Name: | N-Hydroxysuccinimide |
Synonyms: | N-HYDROXY-2,5-PYRROLIDINEDIONE;NHS;N-HYDROXYSUCCINIMDE;N-HYDROXYSUCCINIMIDE;N-HYDROXYSUCCINIMIDE POLYMER-BOUND;1-hydroxy-5-pyrrolidinedione;1-Hydroxysuccinimide;5-Pyrrolidinedione,1-hydroxy-2 |
CAS: | 6066-82-6 |
MF: | C4H5NO3 |
MW: | 115.09 |
EINECS: | 228-001-3 |
Product Categories: | Peptide coupling agents;Medical Intermediates;Heterocycles;Other Reagents;Miscellaneous Reagents;Biochemistry;Condensation & Active Esterification;Coupling Reactions (Peptide Synthesis);N-Substituted Maleimides, Succinimides & Phthalimides;N-Substituted Succinimides;Peptide Synthesis;Synthetic Organic Chemistry;Coupling ReagentsSynthetic Reagents;Coupling;Others;Supported Reagents;Supported Synthesis;APIS;Zero-Length Crosslinker;heteroXlink |
Mol File: | 6066-82-6.mol |
N-Hydroxysuccinimide Chemical Properties |
mp | 95-98 °C(lit.) |
storage temp. | 2-8°C |
Water Solubility | SOLUBLE |
Sensitive | Hygroscopic |
BRN | 113913 |
Stability: | Stable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides, strong bases. Protect from moisture. |
CAS DataBase Reference | 6066-82-6(CAS DataBase Reference) |
NIST Chemistry Reference | N-hydroxylsuccinimide(6066-82-6) |
EPA Substance Registry System | 2,5-Pyrrolidinedione, 1-hydroxy-(6066-82-6) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 22-24/25-26-36 |
WGK Germany | 3 |
Hazard Note | Irritant |
HS Code | 29251995 |
MSDS Information |
Provider | Language |
---|---|
1-Hydroxy-2,5-pyrrolidinedione | English |
SigmaAldrich | English |
ACROS | English |
ALFA | English |
N-Hydroxysuccinimide Usage And Synthesis |
Chemical Properties | White to pale yellow |
Usage | Additive used in the carbodiimide method for improved amidations and peptide couplings. |
N-Hydroxysuccinimide Preparation Products And Raw materials |
Raw materials | Hydroxylamine hydrochloride-->Succinic anhydride |
Preparation Products | Enalapril-->Imidapril-->N-ACRYLOXYSUCCINIMIDE-->Arbekacin-->Aspoxicillin-->GUSPERIMUS |