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CAS NO.60-54-8
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Tetracycline Basic information |
Product Name: | Tetracycline |
Synonyms: | 12,12a-pentahydroxy-6-methyl-1,11-dioxo-1;4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-Naphthacenecarboxamide;4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-4-(dimethylamino)-4;6-methyl-1,11-dioxy-2-naphthacenecarboxamide;abramycin;abricycline;achromycin(naphthacenederivative);achromycin(naphthracenederivatives) |
CAS: | 60-54-8 |
MF: | C22H24N2O8 |
MW: | 444.44 |
EINECS: | 200-481-9 |
Product Categories: | Antibiotic Explorer;Intermediates & Fine Chemicals;Pharmaceuticals;Antibacterial;Antibiotics;Antibiotics A to;Antibiotics by Application;Antibiotics T-ZAntibiotics;Chemical Structure Class;Genetic Marker SelectionAntibiotics;Interferes with Protein SynthesisSpectrum of Activity;L - ZAntibiotics;Mechanism of Action;Tetracyclines;Peptide Synthesis/Antibiotics;Inhibitors |
Mol File: | 60-54-8.mol |
Tetracycline Chemical Properties |
mp | 175-177 °C(lit.) |
storage temp. | 2-8°C |
Merck | 13,9271 |
CAS DataBase Reference | 60-54-8(CAS DataBase Reference) |
NIST Chemistry Reference | Tetracycline(60-54-8) |
EPA Substance Registry System | 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5, 5a,6,11,12a-octahydro-3,6, 10,12,12a-pentahydroxy-6- methyl-1,11-dioxo-, (4S,4aS,5aS,6S,12aS)-(60-54-8) |
Safety Information |
Hazard Codes | Xn,Xi |
Risk Statements | 22-36/37/38 |
Safety Statements | 22-36-26 |
WGK Germany | 3 |
RTECS | QI8750000 |
F | 3-8-10 |
HS Code | 29413000 |
Hazardous Substances Data | 60-54-8(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
Tetracycline Usage And Synthesis |
Chemical Properties | Crystalline Solid |
Usage | antibactierial |
Usage | antibacterial, antiamebic, antirickettsial |
Usage | Tetracycline is a linear, tetracyclic, broad spectrum antibiotic first prepared chemically by dechlorination of chlortetracycline and subsequently isolated from several Streptomyces species. Tetracycline has broad spectrum antibacterial and antiprotozoan activity, and acts by binding to the 30S and 50S ribosomal subunits blocking protein synthesis. Tetracycline is a pigment and, like many pigments, is degraded by light, oxygen, trace metal ions and pH variations. The purity of tetracycline is often variable, with significant levels of degradation products. |
Usage | Antibiotic substance produced by Streptomyces spp. Antiamebic; antibacterial; antirickettsial |
Tetracycline Preparation Products And Raw materials |