Keywords

• Probenecid
• 57-66-9
• C13H19NO4S

Quick Details

• ProName: Probenecid 57-66-9
• CasNo: 57-66-9
• Molecular Formula: C13H19NO4S
• Appearance: detailed in specifcations
• Application: Aripiprazole Intermediate
• DeliveryTime: within 5days
• PackAge: as needed
• Port: China main port
• ProductionCapacity: 500 Metric Ton/Month
• Purity: 99%
• Storage: Keep in dry and cool condition
• Transportation: by air or sea
• LimitNum: 1 Kilogram
• MF: C13H21O3PS

Superiority

Our Services

1.Certificate Of Analysis (COA)

2.Material Safety Data Sheet (MSDS)

3.Route of synthesis (ROS)

4.Method of Aanlysis (MOA)

5.Nuclear Magnetic Resonance (NMR)

6.Packing pictures and loading video before loading

7.Free Sample

9.Factory audit

10.Strong after-sale service

Company information

Henan Sunlake Enterprise Corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas.We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you better with our high - quality products and professional team.We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.We welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate.

Details

Probenecid Basic information

Anti-gout drug Indications Adverse reactions Chemical Properties Application Production methods

Product Name:	Probenecid
Synonyms:	4-((dipropylamino)sulfonyl)-benzoicaci;4-(Dipropylsulfamoyl)benzoic acid;4-(dipropylsulfamoyl)benzoicacid;4-[(dipropylamino)sulfonyl]-benzoicaci;Apurina;benacen;Benemid;benemide
CAS:	57-66-9
MF:	C13H19NO4S
MW:	285.36
EINECS:	200-344-3
Product Categories:	Miscellaneous;API;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;API's;Vanilloid/TRPV channel;chemical additive;pharmaceutical intermediate;PROBENEMID;pharmaceutical chemicals;Pharmaceutical raw materials
Mol File:	57-66-9.mol

Probenecid Chemical Properties

mp	194-196°C
storage temp.	Store at RT
Water Solubility	<0.1 g/100 mL at 20 ºC
Merck	14,7754
Stability:	Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
CAS DataBase Reference	57-66-9(CAS DataBase Reference)
NIST Chemistry Reference	P-(dipropylsulfamoyl) benzoic acid(57-66-9)
EPA Substance Registry System	Benzoic acid, 4-[(dipropylamino)sulfonyl]- (57-66-9)

Safety Information

Hazard Codes	Xn
Risk Statements	22-40
Safety Statements	36/37
RIDADR	3249
WGK Germany	3
RTECS	DG9400000
Hazardous Substances Data	57-66-9(Hazardous Substances Data)

MSDS Information

Provider	Language
4-[(Dipropylamino)sulfonyl]benzoic acid	English
SigmaAldrich	English
ALFA	English

Probenecid Usage And Synthesis

Anti-gout drug

Probenecid is a chemically synthetic sulfa anti-gout drug, also known as oxybenzone sulfonamides, which has dual role of both promoting the excretion of uric acid excretion and inhibiting the excretion of penicillin. Clinically it is used for treating chronic gout and suppressing excretion of penicillin-type drugs in order to increase their clinical plasma concentration as an adjuvant drug of penicillin therapy. Its mechanism of action is inhibiting the re-absorption of renal tubular on uric acid, thus increasing uric acid excretion and further lowering plasma uric acid concentration for reducing the deposition of urate in tissues and prevent the crystallization of urate. This product can also promote the dissolution of the pre-formed urate, thereby reducing its damage on the joint. In addition, the product can also competitively inhibit the secretion of a weak organic acid (such as penicillin, cephalosporins) in the renal tubules, which can increase blood concentrations of these antibiotics and prolong their duration of action. This product is easy for oral administration