Product information

 

Torasemide Basic information

Diuretics Application

Product Name:	Torasemide
Synonyms:	AC-4464;1-[4-(3-methylphenyl)aminopyridin-3-yl]sulfonyl-3-propan-2-yl-urea;DEMADEX;JDL-464;BM-02015;LUPLAC;N-[[(1-METHYLETHYL)AMINO]CARBONYL]-4-[(3-METHYLPHENYL)AMINO]-3-PYRIDINESULFONAMIDE;TORADIUR
CAS:	56211-40-6
MF:	C16H20N4O3S
MW:	348.42
EINECS:	200-659-6
Product Categories:	Active Pharmaceutical Ingredients;Diuretic;APIs;Torasemide;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Ion transporter and other ion channel;ANTIZOL
Mol File:	56211-40-6.mol

Torasemide Chemical Properties

mp	163-164°C
storage temp.	-20°C Freezer
Water Solubility	Soluble
Merck	9552
CAS DataBase Reference	56211-40-6(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36-36/37/38
Safety Statements	26-37/39
RTECS	UT7938000

MSDS Information

Provider	Language
Torasemide	English

Torasemide Usage And Synthesis

Diuretics	Diuretics are drugs mainly acting on the kidneys to increase the excretion of water and electrolytes, and increase urine output. Their potency can be divided into: 1. potent diuretics (loop diuretics): including furosemide, bumetanide, ethacrynic acid. 2. Middle efficiency diuretics include: thiazide diuretics, such as hydrochlorothiazide, bendroflumethiazide and so on. 3. Inefficient diuretics include: retention of potassium diuretics spironolactone, triamterene and carbonic anhydrase inhibitor acetazolamide and the like. Potent diuretics effect on medullary loop ramus crude segment medulla,they inhibit reabsorption of active chlorine, followed by inhibiting sodium reabsorption, and play a strong diuretic effect. Torasemide is a potent diuretic, its mechanism of action is similar to furosemide, it has no effect on the proximal tubules, it does not cause an increase in the discharge of potassium. This product increase renal volume and sodium excretion is dose-dependent , it does not affect the calcium and potassium excretion, excretion and metabolism have no association with renal function, large doses have no significant toxicity. Sort diuretic strength by: bumetanide> torasemide> piretanide> furosemide. It is useful in the treatment of acute and chronic renal failure and essential hypertension. Adverse reactions of torasemide are similar to furosemide ,common adverse reactions are headache, dizziness, weakness, nausea, muscle spasms, but it produces lesser extent of potassium loss ,it has no effect on uric acid, blood glucose and lipid . The above information is edited by the chemicalbook of Tian Ye.
Application	It is used as a diuretic.
Chemical Properties	Crystalline Solid
Usage	alcohol dehydrogenase inhibitor, antidote
Usage	Used as a diuretic

Company information

 Henan sunlake enterprise corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .

  Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs ,  Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East ,  Africa , South America and some other countries and areas.

    We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you  better with our high - quality products and professional team.

    We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.

    We  welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate.