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CAS NO.5508-58-7
1(100-500)Kilogram1(500-1000)Kilogram2(1000-2000)Kilogram
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5508-58-7 |
| Andrographolide Basic information |
| Product Name: | Andrographolide |
| Synonyms: | ANDRO;ANDROGRAPHIS;ANDROGRAPHOLIDE;3A,14,15,18-TETRAHYDROXY-5B,9B,H,10A-LAMBDA-8,20-DIENE;2(3H)-FURANONE,3-[2-[(1R,4AS,5R,6R,8AS)-DECAHYDRO-6-HYDROXY-5-(HYDROXYMETHYL)-5,8A-DIMETHYL-2-METHYLENE-1-NAPHTHALENYL]ETHYLIDENE]DIHYDRO-4-HYDROXY-, (3E,4S)-;2(3h)-furanone,3-(2-(decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-met;5-alpha,6-alpha,8a-alpha))-t;hylene-1-naphthalenyl)ethylidene)dihydro-4-hydroxy-,(1r-(1-alpha(e(s*)),4a-be |
| CAS: | 5508-58-7 |
| MF: | C20H30O5 |
| MW: | 350.45 |
| EINECS: | 226-852-5 |
| Product Categories: | Di-Terpenoids;Asymmetric Synthesis;Chiral Building Blocks;Complex Molecules;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;natural product |
| Mol File: | 5508-58-7.mol |
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| Andrographolide Chemical Properties |
| mp | 229-232 °C(lit.) |
| alpha | -126 º (c=1.5,HAc) |
| Merck | 13,638 |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 22-24/25-36-26 |
| WGK Germany | 3 |
| RTECS | LU3490750 |
| HS Code | 29322980 |
| MSDS Information |
| Provider | Language |
|---|---|
| Andrographolide | English |
| Andrographolide Usage And Synthesis |
| Chemical Properties | colorless Plates |
| Usage | Andrographolide is a labdane diterpenoid. Andrographolide is the main bioactive component isolated from the medicinal plant Andrographis paniculata. Andrographolide showed significant antihepatotoxic action in P. berghei K173- induced hepatic damage in M. natalensis. Andrographolide inhibits tumor necrosis factor-α (TNF-α)-induced intercellular adhesion mol.-1 (ICAM-1) expression and adhesion of HL-60 cells onto human umbilical vein endothelial cells (HUVEC), which are associated with inflammatory diseases. These findings suggest that Andrographolide may have potential as a cardiovascular-protective agent. |
| Usage | antineoplastic |
| Andrographolide Preparation Products And Raw materials |
| Raw materials | Etanol |