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CAS NO.51-49-0
D-Thyroxine Basic information |
Product Name: | D-Thyroxine |
Synonyms: | 3-[4-(P-HYDROXY-3,5-DIIODOPHENOXY)-3,5-DIIODOPHENYL]-D-ALANINE;DEBETROL;D-B-[(3 5-DIIODO-4-HYDROXYPHENOXY)-3 5-DIIODO-PHENYL]ALANINE;D-3,5-DIIODO-4-(3',5'-DIIODO-4'-HYDROXYPHENOXY)-PHENYLALANINE;D-3,3',5,5'-TETRAIODOTHYRONINE;D-3-[4-(4-HYDROXY-3,5-DIIODOPHENOXY)-3,5-DIIODOPHENYL]ALANINE;d-2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]-propanoic acid;D-THYROXINE |
CAS: | 51-49-0 |
MF: | C15H11I4NO4 |
MW: | 776.87 |
EINECS: | 200-102-7 |
Product Categories: | Amino Acids & Derivatives;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals |
Mol File: | 51-49-0.mol |
D-Thyroxine Chemical Properties |
mp | ~235 °C (dec.) |
storage temp. | 2-8°C |
CAS DataBase Reference | 51-49-0(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xn |
Risk Statements | 20/21/22-40 |
Safety Statements | 36/37-36-22 |
WGK Germany | 3 |
F | 8-10 |
MSDS Information |
Provider | Language |
---|---|
D-2-Amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]-propanoic acid | English |
SigmaAldrich | English |
D-Thyroxine Usage And Synthesis |
Chemical Properties | beige to light grey powder |
Usage | One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia. |