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CAS NO.50-28-2
| Estradiol Basic information |
| Product Name: | Estradiol |
| Synonyms: | BETA-ESTRADIOL-16,16,17-D3;17BETA-ESTRADIOL-16,16,17-D3;(+)-3,17β-estradiol;(17b)-estra-1,3,5(10)-triene-3,17diol;(17β)-estra-1,3,5(10)-triene-3,17diol;.alpha.-Oestradiol;.beta.-Oestradiol;17-.beta.-Estra-1,3,5(10)-triene-3,17-diol |
| CAS: | 50-28-2 |
| MF: | C18H24O2 |
| MW: | 272.38 |
| EINECS: | 200-023-8 |
| Product Categories: | Steroids;Estrogen;Hormone;Analytical Chemistry;Biochemistry;Environmental Endocrine Disruptors;Estradiol, etc. (Environmental Endocrine Disruptors);Hydroxysteroids;Intracellular receptor;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;API;VIVELLE;Hormone Drugs;Inhibitors |
| Mol File: | 50-28-2.mol |
|
|
|
| Estradiol Chemical Properties |
| mp | 178-179 °C(lit.) |
| refractive index | 80.4 ° (C=1, Dioxane) |
| storage temp. | 2-8°C |
| form | powder |
| Merck | 14,3703 |
| BRN | 1914275 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 50-28-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Estra-1,3,5(10)-triene-3,17beta-diol(50-28-2) |
| EPA Substance Registry System | Estra-1,3,5(10)- triene-3,17-diol (17.beta.)-(50-28-2) |
| Safety Information |
| Hazard Codes | T,Xn,F |
| Risk Statements | 60-61-45-63-64-40-36-20/21/22-11 |
| Safety Statements | 53-22-36/37/39-45-36/37-26-16 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| RTECS | KG2975000 |
| F | 8-10 |
| HazardClass | 6.1 |
| PackingGroup | III |
| Hazardous Substances Data | 50-28-2(Hazardous Substances Data) |
| MSDS Information |
| Provider | Language |
|---|---|
| 1,3,5-Estratriene-3,17beta-diol | English |
| SigmaAldrich | English |
| Estradiol Usage And Synthesis |
| Chemical Properties | White Crystalline Powder |
| Usage | Potent mammalian estrogenic hormone produced by the ovary. |
| Usage | Estradiol is the major estrogen secreted by the premenopausal ovary. |
| Biological Activity | Endogenous estrogen receptor (ER) agonist (K i values are 0.12 and 0.13 nM for ER α and ER β respectively). Also high affinity ligand at membrane estrogen GPR30 receptors. |
| Estradiol Preparation Products And Raw materials |
| Raw materials | Nitrogen-->p-Toluenesulfonic acid-->Litium-->Potassium borohydride-->Biphenyl-->Acetylacetone-->1,3,5(10)-Estratrien-3-ol-17-one-->Diphenylmethane-->4-ETHYL-2-METHYLPYRIDINE-->ADD |
| Estradiol Basic information |
| Product Name: | Estradiol |
| Synonyms: | BETA-ESTRADIOL-16,16,17-D3;17BETA-ESTRADIOL-16,16,17-D3;(+)-3,17β-estradiol;(17b)-estra-1,3,5(10)-triene-3,17diol;(17β)-estra-1,3,5(10)-triene-3,17diol;.alpha.-Oestradiol;.beta.-Oestradiol;17-.beta.-Estra-1,3,5(10)-triene-3,17-diol |
| CAS: | 50-28-2 |
| MF: | C18H24O2 |
| MW: | 272.38 |
| EINECS: | 200-023-8 |
| Product Categories: | Steroids;Estrogen;Hormone;Analytical Chemistry;Biochemistry;Environmental Endocrine Disruptors;Estradiol, etc. (Environmental Endocrine Disruptors);Hydroxysteroids;Intracellular receptor;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;API;VIVELLE;Hormone Drugs;Inhibitors |
| Mol File: | 50-28-2.mol |
|
|
|
| Estradiol Chemical Properties |
| mp | 178-179 °C(lit.) |
| refractive index | 80.4 ° (C=1, Dioxane) |
| storage temp. | 2-8°C |
| form | powder |
| Merck | 14,3703 |
| BRN | 1914275 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 50-28-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Estra-1,3,5(10)-triene-3,17beta-diol(50-28-2) |
| EPA Substance Registry System | Estra-1,3,5(10)- triene-3,17-diol (17.beta.)-(50-28-2) |
| Safety Information |
| Hazard Codes | T,Xn,F |
| Risk Statements | 60-61-45-63-64-40-36-20/21/22-11 |
| Safety Statements | 53-22-36/37/39-45-36/37-26-16 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| RTECS | KG2975000 |
| F | 8-10 |
| HazardClass | 6.1 |
| PackingGroup | III |
| Hazardous Substances Data | 50-28-2(Hazardous Substances Data) |
| MSDS Information |
| Provider | Language |
|---|---|
| 1,3,5-Estratriene-3,17beta-diol | English |
| SigmaAldrich | English |
| Estradiol Usage And Synthesis |
| Chemical Properties | White Crystalline Powder |
| Usage | Potent mammalian estrogenic hormone produced by the ovary. |
| Usage | Estradiol is the major estrogen secreted by the premenopausal ovary. |
| Biological Activity | Endogenous estrogen receptor (ER) agonist (K i values are 0.12 and 0.13 nM for ER α and ER β respectively). Also high affinity ligand at membrane estrogen GPR30 receptors. |
| Estradiol Preparation Products And Raw materials |
| Raw materials | Nitrogen-->p-Toluenesulfonic acid-->Litium-->Potassium borohydride-->Biphenyl-->Acetylacetone-->1,3,5(10)-Estratrien-3-ol-17-one-->Diphenylmethane-->4-ETHYL-2-METHYLPYRIDINE-->ADD |