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1950-3-3 C23H32O6 Hydrocortisone acetate

CAS NO.50-03-3

  • Min.Order: 10 Gram
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Keywords

  • 1950-3-3 C23H32O6 Hydrocortisone acetate
  • 1950-3-3
  • C23H32O6

Quick Details

  • ProName: 1950-3-3 C23H32O6 ...
  • CasNo: 50-03-3
  • Molecular Formula: C23H32O6
  • Appearance: white powder
  • Application: Biochemistry;Hydroxyketosteroids;Stero...
  • DeliveryTime: 5-7 days after payment
  • PackAge: Woven bag
  • Port: Tianjin Shanghai
  • ProductionCapacity: 1 Kilogram/Day
  • Purity: 99%
  • Storage: Normal temperature
  • Transportation: Ocean shipping Express delivery
  • LimitNum: 10 Gram

Superiority

Hydrocortisone acetate Basic information
Adrenocorticotropic hormone drugs Indications Contraindications Adverse Reactions Precautions Chemical Property Application Production methods
Product Name: Hydrocortisone acetate
Synonyms: (11beta)-21-(Acetoxy)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione;11,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl acetate;11-beta,17-alpha-dihydroxy-21-acetoxypregesterone;11beta17alpha-Dihydroxy-21-acetoxypregesterone;17-alpha-hydrocorticosterone21-acetate;17alpha-Hydrocorticosterone-21-acetate;17-dihydroxy-20-dion(11-beta)-pregn-4-ene-21-(acetoxy)-11;17-dihydroxy-20-dion(11beta)-pregn-4-ene-21-(acetyloxy)-11
CAS: 50-03-3
MF: C23H32O6
MW: 404.5
EINECS: 200-004-4
Product Categories: Biochemistry;Hydroxyketosteroids;Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Veterinaries;Steroid and Hormone;Hormone Drugs;Adrenal cortical hormone drugs;API
Mol File: 50-03-3.mol
Hydrocortisone acetate Structure
 
Hydrocortisone acetate Chemical Properties
mp  223 °C (dec.)(lit.)
Fp  223°C
storage temp.  0-6°C
Decomposition  223 ºC
Merck  14,4787
BRN  2066841
Stability: Stable, but may be light or moisture sensitive. Incompatible with strong oxidizing agents.
CAS DataBase Reference 50-03-3(CAS DataBase Reference)
NIST Chemistry Reference Hydrocortisone acetate(50-03-3)
 
Safety Information
Hazard Codes  Xn,T
Risk Statements  63-10-45
Safety Statements  36/37-45-53
WGK Germany  3
RTECS  GM8960000
MSDS Information
Provider Language
SigmaAldrich English
ALFA English
 
Hydrocortisone acetate Usage And Synthesis
Adrenocorticotropic hormone drugs Hydrocortisone acetate is an adrenal hormone drugs, white crystalline powder, odorless, bitter taste. The melting point is 216 ~ 222 ℃, right optical. Slightly soluble in ethanol, ether, chloroform, acetone, insoluble in water. It was synthesized by In 17α- hydroxy progesterone. 
Hydrocortisone acetate has important physiological activities such as anti-inflammatory, anti-viral, anti-allergic, anti-shock, reducing inflammatory exudation effect, commonly used in clinical adrenal insufficiency and autoimmune diseases. Preparations are injection, tablets, ointments and eye drops. Adding a small amount of hydrocortisone acetate in some cosmetics cortisol can increase the efficacy of anti-allergy and improve the degree of whitening of the skin, but long-term using of such substances can cause the skin produce hormone-dependent disease. Our cosmetics cosmetics specifications prescribedthathormone substances can not be added.
Indications For allergic, non-infectious skin diseases and a number of proliferative skin disorders. Such as dermatitis, eczema, neurodermatitis, seborrheic dermatitis and itching psychosis.

Figure 1 the chemical structure formula of tetra-fluoroethane.
Contraindications 1. This medicine and matrix components allergy and allergic to other glucocorticoids are prohibited.
2. The primary bacterial, fungal and viral infectious skin diseases such as disabledare prohibited.
The above information is edited by the chemicalbook of KuiMing.
Adverse Reactions Long-term using can cause local skin atrophy, telangiectasia, pigmentation, folliculitis, perioral dermatitis and secondary infection.
Precautions 1. Not long-term, large-scale use. 
2. The coated parts such as a burning sensation, itching, swelling, etc., should stop the medication.
Chemical Property White or almost white crystalline powder, odorless. Mp218-221.5 ℃; 25D + 166 ° (dioxane) Specific rotation [α]; ethanol maximum absorption at 240nm wavelength. Insoluble in water, slightly soluble in ethanol (1: 230) and chloroform (1: 150), insoluble in ether.
Application Corticosteroid drugs, have anti-inflammatory, anti-allergic, anti-toxins, anti-shock effect.
Production methods Hydrocortisone and acetic anhydride in pyridine esterification.
Chemical Properties white powder
Usage Glucocorticoid
 
Hydrocortisone acetate Preparation Products And Raw materials
Raw materials Azabenzene-->Hydrocortisone-->Saponin

 

Details

Hydrocortisone acetate Basic information
Adrenocorticotropic hormone drugs Indications Contraindications Adverse Reactions Precautions Chemical Property Application Production methods
Product Name: Hydrocortisone acetate
Synonyms: (11beta)-21-(Acetoxy)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione;11,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl acetate;11-beta,17-alpha-dihydroxy-21-acetoxypregesterone;11beta17alpha-Dihydroxy-21-acetoxypregesterone;17-alpha-hydrocorticosterone21-acetate;17alpha-Hydrocorticosterone-21-acetate;17-dihydroxy-20-dion(11-beta)-pregn-4-ene-21-(acetoxy)-11;17-dihydroxy-20-dion(11beta)-pregn-4-ene-21-(acetyloxy)-11
CAS: 50-03-3
MF: C23H32O6
MW: 404.5
EINECS: 200-004-4
Product Categories: Biochemistry;Hydroxyketosteroids;Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Veterinaries;Steroid and Hormone;Hormone Drugs;Adrenal cortical hormone drugs;API
Mol File: 50-03-3.mol
Hydrocortisone acetate Structure
 
Hydrocortisone acetate Chemical Properties
mp  223 °C (dec.)(lit.)
Fp  223°C
storage temp.  0-6°C
Decomposition  223 ºC
Merck  14,4787
BRN  2066841
Stability: Stable, but may be light or moisture sensitive. Incompatible with strong oxidizing agents.
CAS DataBase Reference 50-03-3(CAS DataBase Reference)
NIST Chemistry Reference Hydrocortisone acetate(50-03-3)
 
Safety Information
Hazard Codes  Xn,T
Risk Statements  63-10-45
Safety Statements  36/37-45-53
WGK Germany  3
RTECS  GM8960000
MSDS Information
Provider Language
SigmaAldrich English
ALFA English
 
Hydrocortisone acetate Usage And Synthesis
Adrenocorticotropic hormone drugs Hydrocortisone acetate is an adrenal hormone drugs, white crystalline powder, odorless, bitter taste. The melting point is 216 ~ 222 ℃, right optical. Slightly soluble in ethanol, ether, chloroform, acetone, insoluble in water. It was synthesized by In 17α- hydroxy progesterone. 
Hydrocortisone acetate has important physiological activities such as anti-inflammatory, anti-viral, anti-allergic, anti-shock, reducing inflammatory exudation effect, commonly used in clinical adrenal insufficiency and autoimmune diseases. Preparations are injection, tablets, ointments and eye drops. Adding a small amount of hydrocortisone acetate in some cosmetics cortisol can increase the efficacy of anti-allergy and improve the degree of whitening of the skin, but long-term using of such substances can cause the skin produce hormone-dependent disease. Our cosmetics cosmetics specifications prescribedthathormone substances can not be added.
Indications For allergic, non-infectious skin diseases and a number of proliferative skin disorders. Such as dermatitis, eczema, neurodermatitis, seborrheic dermatitis and itching psychosis.

Figure 1 the chemical structure formula of tetra-fluoroethane.
Contraindications 1. This medicine and matrix components allergy and allergic to other glucocorticoids are prohibited.
2. The primary bacterial, fungal and viral infectious skin diseases such as disabledare prohibited.
The above information is edited by the chemicalbook of KuiMing.
Adverse Reactions Long-term using can cause local skin atrophy, telangiectasia, pigmentation, folliculitis, perioral dermatitis and secondary infection.
Precautions 1. Not long-term, large-scale use. 
2. The coated parts such as a burning sensation, itching, swelling, etc., should stop the medication.
Chemical Property White or almost white crystalline powder, odorless. Mp218-221.5 ℃; 25D + 166 ° (dioxane) Specific rotation [α]; ethanol maximum absorption at 240nm wavelength. Insoluble in water, slightly soluble in ethanol (1: 230) and chloroform (1: 150), insoluble in ether.
Application Corticosteroid drugs, have anti-inflammatory, anti-allergic, anti-toxins, anti-shock effect.
Production methods Hydrocortisone and acetic anhydride in pyridine esterification.
Chemical Properties white powder
Usage Glucocorticoid
 
Hydrocortisone acetate Preparation Products And Raw materials
Raw materials Azabenzene-->Hydrocortisone-->Saponin
  HenNan sunlake enterprise corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material . 
   Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas. 
    We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you better with our high - quality products and professional team. 
     We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market. We welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!
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