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CAS NO.4936-47-4
1(100-500)Kilogram1(500-1000)Kilogram2(1000-2000)Kilogram
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4936-47-4 |
| Nifuratel Basic information |
| Product Name: | Nifuratel |
| Synonyms: | MACMIROR;5-[(METHYLTHIO)METHYL]-3-[[(5-NITRO-2-FURANYL)METHYLENE]AMINO-]-2-OXAZO-LIDINONE;5-methylthiomethyl-3-(5-nitrofurfurylideneamino)-2-oxazolidone;NIFURATEL;5-((methylthio)methyl)-3-((5-nitrofurfurylidine)amino)-2-oxazolidinon;5-((methylthio)methyl)-3-((5-nitrofurfurylidine)amino)-2-oxazolidinone;l’n-(5-nitro-2-furfurilidene)-3-amino-5-metilmercaptometil-2-ossazolidinone;magmilor |
| CAS: | 4936-47-4 |
| MF: | C10H11N3O5S |
| MW: | 285.28 |
| EINECS: | 225-576-2 |
| Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;APIS;API |
| Mol File: | 4936-47-4.mol |
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| Nifuratel Chemical Properties |
| mp | 176-178°C |
| storage temp. | -20°C Freezer |
| CAS DataBase Reference | 4936-47-4(CAS DataBase Reference) |
| Safety Information |
| Nifuratel Usage And Synthesis |
| The main effects |
Nifuratel is a derivative of nitrofuran , it is a broad spectrum antibiotic with broad-spectrum antimicrobial effect, Nystatin is a polyene antifungal,it has strong effects on trichomoniasis, bacteria, Candida albicans , it plays a strong killing role especially in common pathogens for gynecological infections such as gram-positive and gram-negative bacteria, trichomoniasis, mold, chlamydia and mycoplasma . After oral administration, it is absorbed by gastrointestinal ,most of it is excreted through the kidneys, it has higher concentrations in blood, urine, genital tissues ,so it can have a strong antibacterial effect in the urinary system, and its metabolites still have antibacterial activity, and it is excreted through the urine . Oral nifuratel can be rapidly absorbed, after oral administration of 200mg, the peak plasma concentration is 9.48μg / L in two hours . The animals acute toxicity test proves that in toxicity of the product is mild. Nifuratel indications include: 1, bacterial vaginosis, trichomonas vaginitis, vulvovaginal candidiasis, vaginal mixed infections. 2, urinary tract infections. 3, gastrointestinal amoebiasis and trichomoniasis Jia. The above information is edited by the chemicalbook of Tian Ye. |
| Chemical Properties | Yellow Solid |
| Usage | Nifuratel is a drug used as an antibacterial, antifungal, antiprotozoal (Trichomonas). Nifuratel appears to have a broad antibacterial spectrum of action and is effective against Chlamydia trachomatis and Mycoplasma spp. as well as fungal infections from Candida spp. |