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HENAN SUNLAKE ENTERPRISE CORPORATION

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439081-18-2 C24H25ClFN5O3 BIBW 2992

CAS NO.439081-18-2

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,
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Product Details

Keywords

  • 3-Chloro-4-fluorophenyl
  • Tovok
  • tetrahydrofuran-3-yloxy

Quick Details

  • ProName: 439081-18-2 C24H25ClFN5O3 BIBW 2992
  • CasNo: 439081-18-2
  • Molecular Formula: C24H25ClFN5O3
  • Appearance: As detailed
  • Application: 439081-18-2 ...
  • DeliveryTime: 7-10 days after payment
  • PackAge: As required
  • Port: Shanghai/Tianjin/Qingdao
  • ProductionCapacity: 100-200 Kilogram/Month
  • Purity: 99%
  • Storage: room temperatuure
  • Transportation: By air/sea/express
  • LimitNum: 1 Kilogram
  • Grade: Pharma Grade

Superiority

About Certificate

 

1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)

 

About Service

 

1. Quality control, before shipment, free sample for test.
2. Prompt shipment with professional documents
3. Packing as your request, with photo before shipment
4. Mixed containers with different mixed items in one container

 

About Company

 
HenNan sunlake enterprise corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
     Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs ,  Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East ,  Africa , South America and some other countries and areas.
    We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you  better with our high - quality products and professional team.
    We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.
     We  welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!

Details

Product Name: BIBW 2992
Synonyms: BIBW 2992;N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide;Tovok;Tovok, BIBW 2992;BIBW2992 Afatinib;Afatinib (BIBW 2992);ToMtovok;(S,E)-N-(4-(3-chloro-4-fluorophenylaMino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(diMethylaMino)but-2-enaMide
CAS: 439081-18-2
MF: C24H25ClFN5O3
MW: 485.944
EINECS:  
Product Categories: API;Inhibitors
Mol File: 439081-18-2.mol
BIBW 2992 Structure
 
BIBW 2992 Chemical Properties
density  1.380
 
Safety Information
MSDS Information
 
 
BIBW 2992 Usage And Synthesis
Usage BIBW2992 (Afatinib, Tomtovok, Tovok) irreversibly inhibits EGFR/HER2 including EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively.
 
BIBW 2992 Preparation Products And Raw materials

 

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