HENAN SUNLAKE ENTERPRISE CORPORATION
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Tel: 17734809689
Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
Mobile: 17734809689
Tel: +86-371- 86259723
Fax: +86-371- 86259723
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City: ZHENGZHOU
Street: Mingmen International Center, NO.222 Dongming Road,Zhengzhou,Henan,China
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CAS NO.380843-75-4
1(10-100)Gram1(100-200)Gram
| Bosutinib Basic information |
| Product Name: | Bosutinib |
| Synonyms: | SKI-606;BOSUTINIB;Bosutinib for research;4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile;Bosutinib ( SKI-606 );3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-Methoxyphenyl)aMino]-6-Methoxy-7-[3-(4-Methyl-1-piperazinyl)propoxy]-;Bosutinib(TINIBS );4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile Bosutinib (SKI-606) |
| CAS: | 380843-75-4 |
| MF: | C26H29Cl2N5O3 |
| MW: | 530.45 |
| EINECS: | |
| Product Categories: | API;Aromatics Compounds;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pfizer compounds;Pharmaceuticals |
| Mol File: | 380843-75-4.mol |
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| Bosutinib Chemical Properties |
| mp | 116-120 ºC |
| density | 1.36 |
| storage temp. | room temp |
| CAS DataBase Reference | 380843-75-4(CAS DataBase Reference) |
| Bosutinib Usage And Synthesis |
| Chemical Properties | Pale Yellow Solid |
| Usage | A novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells. |
| Usage | peripheral vasolidator increases cerebral blood flow, potential therapeutic for Altzheimer’s disease, cognitive impairment and dementia |
| Usage | Bosutinib (SKI-606) is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM, respectively. |
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