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Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
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Tel: +86-371- 86259723
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CAS NO.34552-83-5
1(10-100)Metric Ton1(10-100)Metric Ton
| Loperamide hydrochloride Basic information |
| Product Name: | Loperamide hydrochloride |
| Synonyms: | LABOTEST-BB LT00134703;LOSERAMIN;LOPERAMIDE HCL;LOPERAMIDE HYDROCHLORIDE;4-(4-CHLOROPHENYL)-4-HYDROXY-N,N-DIMETHYL-ALPHA,ALPHA-DIPHENYL-1-PIPERIDINBUTYRAMIDE HYDROCHLORIDE;4-(4-CHLOROPHENYL)-4-HYDROXY-N,N-DIMETHYL-ALPHA,ALPHA-DIPHENYL-1-PIPERIDINEBUTANAMIDE HYDROCHLORIDE;4-(4-chlorophenyl)-4-hydroxy-n,n-dimethyl-alpha,alpha-diphenylpiperidine-1-butyramide monohydrochloride;4-[P-CHLOROPHENYL]-4-HYDROXY-N,N-DIMETHYL-ALPHA,ALPHA-DIPHENYL-1-PIPERIDINEBUTYRAMIDE HYDROCHLORIDE |
| CAS: | 34552-83-5 |
| MF: | C29H34Cl2N2O2 |
| MW: | 513.5 |
| EINECS: | 252-082-4 |
| Product Categories: | ACTIVE PHARMACEUTICAL INGREDIENTS;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;Opioid receptor and opioid-like receptor;Amines;Heterocycles;IMODIUM;Other APIs |
| Mol File: | 34552-83-5.mol |
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| Loperamide hydrochloride Chemical Properties |
| mp | 223-225°C |
| storage temp. | Store at RT |
| Merck | 5571 |
| CAS DataBase Reference | 34552-83-5(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | TM4960000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| Loperamide hydrochloride Usage And Synthesis |
| Chemical Properties | White Solid |
| Usage | Labeled Loperamide, which is used as an antidiarrheal |
| Usage | Ca channel blocker |
| Biological Activity | High affinity μ -opioid receptor agonist with peripheral selectivity (K i values are 2, 48 and 1156 nM for μ -, δ - and κ -opioid receptors respectively). Antidiarrhoeal and antihyperalgesic agent. Also a Ca 2+ channel blocker; at low micromolar concentrations it blocks broad spectrum neuronal HVA Ca 2+ channels and at higher concentrations it reduces Ca 2+ flux through NMDA receptor operated channels. |
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