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CAS NO.303-26-4
| 1-(4-Chlorobenzhydryl)piperazine Basic information |
| Product Name: | 1-(4-Chlorobenzhydryl)piperazine |
| Synonyms: | 1-((4-chlorophenyl)phenylmethyl)-piperazin;1-(4-Chloro-alpha-phenylbenzyl)piperazine;1-(alpha-Phenyl-4-chlorobenzyl)piperazine;1-(p-chloro-alpha-phenylbenzyl)-piperazin;4-(4-Chlorobenzhydryl)piperazine;Norchlorcyclizine;Piperazine, 1-(alpha-(4-chlorophenyl)benzyl)-;Piperazine, 1-(p-chloro-alpha-phenylbenzyl)- |
| CAS: | 303-26-4 |
| MF: | C17H19ClN2 |
| MW: | 286.8 |
| EINECS: | 206-137-4 |
| Product Categories: | Heterocycles;Piperazine derivates;API intermediates;Aromatics;Metabolites & Impurities;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Piperazines;PiperazinesHeterocyclic Building Blocks;Intermediates & Fine Chemicals;Pharmaceuticals;C15 to C30;Building Blocks;C16 to C29;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks |
| Mol File: | 303-26-4.mol |
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| 1-(4-Chlorobenzhydryl)piperazine Chemical Properties |
| Melting point | 65-70 °C(lit.) |
| Boiling point | 178-180 °C0.5 mm Hg(lit.) |
| Fp | >230 °F |
| storage temp. | Refrigerator |
| CAS DataBase Reference | 303-26-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-(303-26-4) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39-24/25 |
| WGK Germany | 3 |
| RTECS | TL1772000 |
| Hazard Note | Irritant |
| MSDS Information |
| Provider | Language |
|---|---|
| 1-(4-Chlorobenzhydryl)piperazine | English |
| SigmaAldrich | English |
| ACROS | English |
| 1-(4-Chlorobenzhydryl)piperazine Usage And Synthesis |
| Chemical Properties | White Solid |
| Usage | A metabolite of Cetirizine and Hydroxyzine |
| Usage | A metabolite of Cetirizine (C281100) and Hydroxyzine. Citirizine impurity A. |
| Usage | Cetrizine Dihydrochloride intermediate |
| 1-(4-Chlorobenzhydryl)piperazine Preparation Products And Raw materials |
| Raw materials | Ethyl acetate-->Methanol-->Dichloromethane-->Thionyl chloride-->PETROLEUM ETHER-->Toluene-->Potassium carbonate-->Magnesium sulfate-->Ammonium hydroxide-->1,4-Diazacyclohexane-->Calcium chloride-->Potassium iodide-->2-Butanone-->4-Chlorobenzhydrol |
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