HENAN SUNLAKE ENTERPRISE CORPORATION
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Tel: +86-371- 86259723
Tel: 17734809689
Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
Mobile: 17734809689
Tel: +86-371- 86259723
Fax: +86-371- 86259723
Province/state: HENAN
City: ZHENGZHOU
Street: Mingmen International Center, NO.222 Dongming Road,Zhengzhou,Henan,China
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CAS NO.21679-14-1
1(100-500)Kilogram1(500-1000)Kilogram2(1000-2000)Kilogram
1. ISO 9001 approved, GMP producing standard,Proffesional QA system, our quality is guaranteed.
2. Facotory direct sale, most comptive price ensured;
3. Audited Supplier on lookchem, No trick, No Scam!
4. Enough stock can make sure safe delivery.
5. Complete before and after sale service, welcome your questions and glad to help.
Offer 21679-14-1
PRODUCT INFORMATION :
| Fludarabine Basic information |
| Product Name: | Fludarabine |
| Synonyms: | 2-Fluoroadeninearabinoside;9-beta-d-arabinofuranosyl-2-fluoro-9h-purin-6-amin;9-beta-d-arabinofuranosyl-2-fluoro-adenin;f-ara-a;6-AMINO-9 BETA-D-ARABINOFURANOSYLFLUOROPURINE;9-bata-d-arabinofuranosyl-2-fluoroadenine;9-BETA-D-ARABINOFURANOSYL-2-FLUORO-9H-PURIN-6-AMINE;9-BETA-D-ARABINOFURANOSYL-2-FLUOROADENINE |
| CAS: | 21679-14-1 |
| MF: | C10H12FN5O4 |
| MW: | 285.23 |
| EINECS: | 244-525-5 |
| Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;API;F-ara-A, NSC 118218;Anti-cancer&immunity;Inhibitors |
| Mol File: | 21679-14-1.mol |
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| Fludarabine Chemical Properties |
| mp | 265-268°C |
| storage temp. | 2-8°C |
| solubility | DMF: 20 mg/mL, clear, faintly yellow |
| Merck | 13,4152 |
| CAS DataBase Reference | 21679-14-1(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 23/24/25-36/37/38-39/23/24/25-39-22 |
| Safety Statements | 26-36/37-45 |
| WGK Germany | 3 |
| RTECS | AU6207000 |
| F | 10 |
| Hazardous Substances Data | 21679-14-1(Hazardous Substances Data) |
| MSDS Information |
| Provider | Language |
|---|---|
| 9-bata-D-Arabinofuranosyl-2-fluoroadenine | English |
| SigmaAldrich | English |
| Fludarabine Usage And Synthesis |
| Chemical Properties | White Solid |
| Usage | Used as an antineoplastic |
| Usage | A STAT-1 activation inhibitor and a DNA synthesis inhibitor. |
| Usage | phosphate as antineoplastic;inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase |
| Usage | Irreversible muscarinic agonist |
| Usage | DNA synthesis and methylation inhibitor;A cell permeable agent that interferes with DNA synthesis and repair; also inhibits RNA transcription |
| Biological Activity | Purine analog that inhibits DNA synthesis. Exhibits antiproliferative activity (IC 50 = 1.54 μ M in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP and survivin expression. Displays anticancer activity against hematological malignancies in vivo . |
| Fludarabine Preparation Products And Raw materials |
| Raw materials | Acetic anhydride-->Fluoroboric acid-->Boron trichloride -->2,4,5,6-TETRAAMINOPYRIMIDINE-->2,6-Diaminopurine-->DIACETAMIDE |
1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.
2. Quality assurance: we have a first-class testing equipment and testing personnel, in strict accordance with ISO and cGMP standards, ensure that the quality of the shipment.
3.Ultra-low prices, we follow the meager profit but high turnover principle to win more customers, to provide you with quality and cheap products.
4.The best service: we can real-time quotation, tracking service, ensure the safety of the goods to the clients.
5. Customer groups: our clients throughout the world more than 30 countries, high quality products, low price, best service to win the customer's consistent high praise.
If you demand the product, you are welcome to contact us at any time, we guarantee that you seriously every inquiry, give you the fastest reply and the best service.