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Country: China (Mainland)
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Tel: 17734809689
Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
Mobile: 17734809689
Tel: +86-371- 86259723
Fax: +86-371- 86259723
Province/state: HENAN
City: ZHENGZHOU
Street: Mingmen International Center, NO.222 Dongming Road,Zhengzhou,Henan,China
MaxCard:
CAS NO.1953-54-4
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5-Hydroxyindole Basic information |
Product Name: | 5-Hydroxyindole |
Synonyms: | 5-Hydroxy-1H-indole;Hydroxy-5 indole;hydroxy-5indole;TIMTEC-BB SBB004214;1H-INDOL-5-OL;5-HYDROXYINDOLE;5-INDOLOL;INDOL-5-OL |
CAS: | 1953-54-4 |
MF: | C8H7NO |
MW: | 133.15 |
EINECS: | 217-782-6 |
Product Categories: | blocks;IndolesOxindoles;indole derivative;Indoles and derivatives;pharmacetical;Indole;Indoles;Simple Indoles;Building Blocks;C7 to C9;Chemical Synthesis;Heterocyclic Building Blocks;Heterocycle-Indole series |
Mol File: | 1953-54-4.mol |
5-Hydroxyindole Chemical Properties |
mp | 106-108 °C(lit.) |
storage temp. | 0-6°C |
color | beige |
Sensitive | Light Sensitive |
BRN | 112349 |
CAS DataBase Reference | 1953-54-4(CAS DataBase Reference) |
NIST Chemistry Reference | Indol-5-ol(1953-54-4) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36-37/39 |
WGK Germany | 3 |
RTECS | NM2430000 |
HazardClass | IRRITANT, KEEP COLD |
HS Code | 29339990 |
MSDS Information |
Provider | Language |
---|---|
5-Hydroxyindole | English |
ACROS | English |
SigmaAldrich | English |
ALFA | English |
5-Hydroxyindole Usage And Synthesis |
Chemical Properties | beige to brown crystalline needles or powder |
Usage | • ;Reactant for preparation of (oxoimidazolidinyl/oxopyrimidinyl)benzenesulfonates as antitumor agents and tubulin inhibitors1• ;Reactant for preparation of anthranilic acids2• ;Reactant for preparation of indole compounds as dopamine D2 receptor antagonists3• ;Reactant for preparation of naphthalimide- or carbazole-containing human β-adrenoceptor ligands4• ;Reactant for preparation of melanins as nature-inspired radioprotectors5• ;Reactant for preparation of 5-vinyl-3-pyridinecarbonitriles as PKCθ inhibitors6 |
Usage | 5-Hydroxyindole is a hydroxylated indole used as a building block in the preparation of various pharmaceutical compounds such as indole based neurochemicals. 5-Hydroxyindole is a metabolite of Tryptop han (T894800). 5-Hydroxyindole displayed weak inhibitory activity on human melanoma tyrosinase. 5-Hydroxyindole also showed inhibition of serotonin transport by blood platelets. |
5-Hydroxyindole Preparation Products And Raw materials |
Raw materials | Palladium-->N,N-Dimethylformamide dimethyl acetal-->Benzyl bromide-->Red prussiate-->3-Methyl-4-nitrophenol |