HENAN SUNLAKE ENTERPRISE CORPORATION
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Tel: +86-371- 86259723
Tel: 17734809689
Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
Mobile: 17734809689
Tel: +86-371- 86259723
Fax: +86-371- 86259723
Province/state: HENAN
City: ZHENGZHOU
Street: Mingmen International Center, NO.222 Dongming Road,Zhengzhou,Henan,China
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CAS NO.193079-69-5
| Tabimorelin Basic information |
| Product Name: | Tabimorelin |
| Synonyms: | Tabimorelin;Tabimorelin [inn];Unii-L51cbe03kf;N-[(2E)-5-Amino-5-methyl-1-oxo-2-hexenyl]-N-methyl-3-(2-naphthalenyl)-D-alanyl-N,Nα-dimethyl-D-phenylalaninamidehemifumarate |
| CAS: | 193079-69-5 |
| MF: | 2C32H40N4O3.C4H4O4 |
| MW: | 1173.46 |
| EINECS: | |
| Product Categories: | Amines;Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol File: | 193079-69-5.mol |
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| Tabimorelin Chemical Properties |
| storage temp. | Desiccate at RT |
| Tabimorelin Usage And Synthesis |
| Usage | NN703 (Tabimorelin) is an orally active growth hormone (GH) secretagogue intended for use as an alternative to daily injections of GH. In vitro studies in human liver microsomes have indicated that NN703 is a mechanism-based inhibitor of CYP3A4. |
| Biological Activity | Potent, orally active ghrelin receptor (GHS-R1a) agonist (K i = 50 nM at human recombinant GHS-R1a). Stimulates GH release from rat pituitary cells with an EC 50 value of 2.7 nM. Induces hyperphagia and adiposity in lean rats, but not in leptin signaling-deficient ZDF rats. |
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