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HENAN SUNLAKE ENTERPRISE CORPORATION

Country: China (Mainland)

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162635-04-3 C56H87NO16 Temsirolimus

CAS NO.162635-04-3

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,
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Product Details

Keywords

  • TEMSIROLIMUS
  • 2-methylpropanoate
  • Methylpropionic acid

Quick Details

  • ProName: 162635-04-3 C56H87NO16 Temsirolimus
  • CasNo: 162635-04-3
  • Molecular Formula: C56H87NO16
  • Appearance: White Solid
  • Application: 162635-04-3 ...
  • DeliveryTime: 7-10 days after payment
  • PackAge: As required
  • Port: Shanghai/Tianjin/Qingdao
  • ProductionCapacity: 100-200 Kilogram/Month
  • Purity: 99%
  • Storage: Store at -20°C
  • Transportation: By air/sea/express
  • LimitNum: 1 Kilogram
  • Grade: Pharma Grade

Superiority

About Certificate

 

1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)

 

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1. Quality control, before shipment, free sample for test.
2. Prompt shipment with professional documents
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4. Mixed containers with different mixed items in one container

 

About Company

 
HenNan sunlake enterprise corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
     Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs ,  Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East ,  Africa , South America and some other countries and areas.
    We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you  better with our high - quality products and professional team.
    We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.
     We  welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!

Details

Product Name: Temsirolimus
Synonyms: TEMSIROLIMUS;CCL-779;Rapamycin 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate;42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]rapamycin;C15182;TeMsiroliMus (CCI-779, Torisel);rapaMycin 42-ester with 3-hydroxy-2-(hydroxyMethyl)-2-Methylpropionic acid;TeMsiroliMus (Torisel)
CAS: 162635-04-3
MF: C56H87NO16
MW: 1030.29
EINECS:  
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;CCI-779, NSC 683864;Anti-cancer&immunity;PI3K/Akt/mTOR;Antineoplastic protein kinase inhibitors;mTOR inhibitor;Inhibitors
Mol File: 162635-04-3.mol
Temsirolimus Structure
 
Temsirolimus Chemical Properties
mp  99-101°C
storage temp.  -20°C Freezer
 
Safety Information
MSDS Information
 
 
Temsirolimus Usage And Synthesis
Chemical Properties White Solid
Usage Ester analog of Rapamycin
Usage Temsirolimus (CCI-779) is a specific mTOR inhibitor with IC50 of 1.76 μM.
Usage Temsirolimus is a semisynthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group with a protected bis(dihydromethyl)propionic acid, followed by deprotection. Like all tacrolimus analogues, temsirolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing it from interacting with target proteins. Temsirolimus is extensively cited in the literature with over 700 citations.
Usage Temsirolimus is a semisynthetic macrocyclic lactone prepared from rapamycin by selective acylation of the 42-hydroxy group with a protected bis(dihydromethyl)propionic acid, followed by deprotection. Like all tacrolimus analogues, temsirolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing it from interacting with target proteins. Temsirolimus is extensively cited in the literature with over 700 citations.
 
Temsirolimus Preparation Products And Raw materials

 

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