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CAS NO.141732-76-5
Exenatide acetate Basic information |
Product Name: | Exenatide acetate |
Synonyms: | EXENATIDE ACETATE;ENFUVIRTIDE ACETATE;Exenatide;His-Gly-Gly-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH{2};EXENATIDE ACETATE(EXENDIN-4);Extendin-4;Unii-9p1872D4ol;His-Gly-Gly-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 |
CAS: | 141732-76-5 |
MF: | C186H284N50O62S |
MW: | 4244.60796 |
EINECS: | |
Product Categories: | Peptide;Agonist;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals |
Mol File: | 141732-76-5.mol |
Exenatide acetate Chemical Properties |
CAS DataBase Reference | 141732-76-5(CAS DataBase Reference) |
Safety Information |
Exenatide acetate Usage And Synthesis |
Chemical Properties | White Solid |
Usage | A 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus. Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide has found use as a medication of diabetes II. |
Exenatide acetate Preparation Products And Raw materials |