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CAS NO.124750-99-8
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Losartan potassium Basic information |
Product Name: | Losartan potassium |
Synonyms: | 2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOL-5YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOL;2-butyl-4-chloro-1-[[2'-(1h-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1h-imidazole-5-methanol monopotassium salt;2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOLE-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOL, POTASSIUM SALT;COZAAR;DUP 753;LOSARTAN MONOPOTASSIUM SALT;LOSARTAN POTASSIUM;LOSARTAN POTASSIUM SALT |
CAS: | 124750-99-8 |
MF: | C22H23ClKN6O |
MW: | 462.01 |
EINECS: | 200-287-4 |
Product Categories: | Hypertension;Intermediates & Fine Chemicals;Pharmaceuticals;Losartan;APIS;Aromatics;Heterocycles;API Reference Standard;COZAAR;Cardiovascular APIs;API |
Mol File: | 124750-99-8.mol |
Losartan potassium Chemical Properties |
mp | 263-265°C |
storage temp. | Desiccate at RT |
CAS DataBase Reference | 124750-99-8(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36/37/39 |
RTECS | NI6755100 |
Hazardous Substances Data | 124750-99-8(Hazardous Substances Data) |
Losartan potassium Usage And Synthesis |
Chemical Properties | White to Off-White Crystalline Powder |
Usage | A nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive. |
Usage | antihypertensive, AT1 angiotensin II antagonist |
Usage | Coronary vasodilator used in the diagnosis of coronary heart disease (adenosine A2A agonist). |
Biological Activity | Selective non-peptide angiotensin AT 1 receptor antagonist. Inhibits the contractile effects of angiotensin II on rabbit aorta and jugular vein (pA 2 = 8.27). Orally active antihypertensive agent. |