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Quetiapine fumarate

CAS NO.111974-72-2

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  • Min.Order: 100 Gram
  • Payment Terms: L/C,D/A,D/P,T/T,Other
  • Available Specifications:

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Product Details

Keywords

  • Quetiapine Fumarate main intermediates
  • SEROQUEL
  • Pharmaceutical raw materials

Quick Details

  • ProName: Quetiapine fumarate
  • CasNo: 111974-72-2
  • Molecular Formula: C46H54N6O8S2
  • Appearance: white crystalline powder
  • Application: 111974-72-2 A non-classical antipsych...
  • DeliveryTime: Within 7 working days since received y...
  • PackAge: 1g;5g;10g;25g;50g;100g;500g;1KG;5KG,25...
  • Port: Any Chinese main ports
  • ProductionCapacity: 100 Kilogram/Month
  • Purity: 99%
  • Storage: 2-8, cold storage, to avoid light stor...
  • Transportation: BY SEA /BY AIR /BY COURIER
  • LimitNum: 100 Gram
  • Heavy metal: NULL
  • Grade: Industrial Grade,Food Grade,Pharma Gra...
  • Valid Period: 6 month
  • Application: Multipurpose intermediate
  • Certification: ISO/9001 Certificate

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Quetiapine fumarate Basic information
Antipsychotics Chemical properties Application
Product Name: Quetiapine fumarate
Synonyms: SEROQUEL;QUETIAPINE FUMARATE;QUETIAPINE HEMIFUMARATE;2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate;DIBENZOTHIAZEPINOHONEP;ICI-204636;QUETIAPINE FUMARATE, 99+%;Quetiapine Fumarate main intermediates
CAS: 111974-72-2
MF: C46H54N6O8S2
MW: 883.09
EINECS:  
Product Categories: Active Pharmaceutical Ingredients;Antipsychotic;Intermediates & Fine Chemicals;Pharmaceuticals;Quetiapine;API;Pharmaceutical raw materials;bulk drug material;Inhibitors
Mol File: 111974-72-2.mol
Quetiapine fumarate Structure
 
Quetiapine fumarate Chemical Properties
mp  174-176°C
storage temp.  -20°C Freezer
CAS DataBase Reference 111974-72-2(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xn,N,T,F
Risk Statements  22-50/53-52/53-39/23/24/25-23/24/25-11
Safety Statements  60-61-45-36/37-16
MSDS Information
 
 
Quetiapine fumarate Usage And Synthesis
Antipsychotics Quetiapine fumarate is an antipsychotic, successfully developed by the AstraZeneca United States, it interacts with a variety of neurotransmitter receptors, in the brain, it displays high degree affinity for serotonin (5-HT2) receptor, and it is greater than dopamine D1 and D2 dopamine receptor affinity in the brain. Quetiapine also has high affinity for histamine H1 receptor and adrenergic α1 receptors, and low affinity for α2 receptors, but it basically displays no affinity for cholinergic muscarinic receptors or benzodiazepine receptors . It shows positive results in antipsychotic activity assays such as conditioned avoidance reflex . In clinical, it is mainly used in treatment for adults with severe depression, acute manic episodes of bipolar disorder and schizophrenia of different types . It is not only effective for the positive symptoms of schizophrenia, but also having a certain effect for negative symptoms . It can also alleviate affective symptoms associated with schizophrenia, such as depression, anxiety symptoms and cognitive deficits. 
The above information is edited by the chemicalbook of Tian Ye.
Chemical properties White crystalline powder.
Application A non-classical antipsychotics.
Chemical Properties White Crystalline Solid
Usage Used as an antipsychotic. Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties
Usage antihypertensive adrenergic receptor blocking agent with selective alpha1- and nonselective beta-adrenergic receptor blocking actions in a single substance.

 

 

 

 

 

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C6H6O2

 

 
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