Keywords

• Fasudil hydrochloride
• 105628-07-7
• C14H18ClN3O2S

Quick Details

• ProName: Fasudil hydrochloride 105628-07-7
• CasNo: 105628-07-7
• Molecular Formula: C14H18ClN3O2S
• Appearance: detailed in specifcations
• Application: Aripiprazole Intermediate functional...
• DeliveryTime: within 5days
• PackAge: as needed
• Port: China main port
• ProductionCapacity: 500 Metric Ton/Month
• Purity: 99%
• Storage: Keep in dry and cool condition
• Transportation: by air or sea
• LimitNum: 1 Kilogram
• MF: C13H21O3PS

Superiority

Our Services

1.Certificate Of Analysis (COA)

2.Material Safety Data Sheet (MSDS)

3.Route of synthesis (ROS)

4.Method of Aanlysis (MOA)

5.Nuclear Magnetic Resonance (NMR)

6.Packing pictures and loading video before loading

7.Free Sample

9.Factory audit

10.Strong after-sale service

Company information

Henan Sunlake Enterprise Corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas.We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you better with our high - quality products and professional team.We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.We welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate.

Details

Product Name:	Fasudil hydrochloride
Synonyms:	1-(5-ISOQUINOLINYLSULFONYL)HOMOPIPERAZINE DIHYDROCHLORIDE;1-(5-ISOQUINOLINESULFONYL)-1H-HEXAHYDRO-1,4-DIAZEPINE, DIHYDROCHLORIDE;1-(5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE 2HCL;1-(5-ISOQUINOLINESULFONYL)-HOMOPIPERAZINE DIHYDROCHLORIDE;1-(5-ISOQUINOLINESULFONYL)-HOMOPIPERAZINE HCL;1-(5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE HYDROCHLORIDE;(5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE, 2HCL;5-(1,4-DIAZEPAN-1-YLSULFONYL)ISOQUINOLINE HYDROCHLORIDE
CAS:	105628-07-7
MF:	C14H18ClN3O2S
MW:	327.83
EINECS:
Product Categories:	APIs;API;Inhibitor;Cardiovascular & Blood System Agents;Inhibitors
Mol File:	105628-07-7.mol

Fasudil hydrochloride Chemical Properties

solubility	H2O: >200 mg/mL
form	solid
color	white
CAS DataBase Reference	105628-07-7(CAS DataBase Reference)

Safety Information

WGK Germany	3
RTECS	HM4031166

MSDS Information

Provider	Language
SigmaAldrich	English

Fasudil hydrochloride Usage And Synthesis

Outline

Fasudil hydrochloride is a novel drug having a wide range of pharmacological effects ,it is first developed by Asahi Kasei Corporation, in June 1995 it was listed for the first time in Japan. It is Ratified by China in 2001,that Asahi Kasei Corporation imports fasudil hydrochloride injection under the trade name " Eril." Its molecular structure is 5-isoquinoline sulfonamide derivative,it is RHO kinase inhibitor, by increasing the myosin light chain phosphatase activity it can dilate blood vessels, reduce the tension of endothelial cells, improve brain microcirculation, and does not produce and aggravate Pirates of the brain blood, and it can antagonize inflammatory cytokines, anti-apoptotic neuroprotective, and promote nerve regeneration. Fasudil hydrochloride has a certain effect on promoting the recovery of nerve function, reducing symptoms and reducing morbidity . at the grassroots level due to the constraints of economic conditions and the level of awareness of the disease, ultra-early thrombolytic therapy can not be achieved, but in order to reduce further progression of the disease within the therapeutic window of time, to rebuild local blood circulation is critical, and Fasudil hydrochloride has significant neuroprotective and therapeutic effects