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Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
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Tel: +86-371- 86259723
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CAS NO.1012054-59-9
CUDC-101 Basic information |
Product Name: | CUDC-101 |
Synonyms: | CUDC101;CUDC-101;7-[[4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yl]oxy]-N-hydroxyheptanamide;HeptanaMide, 7-[[4-[(3-ethynylphenyl)aMino]-7-Methoxy-6-quinazolinyl]oxy]-N-hydroxy-;7-[[4-[(3-Ethynylphenyl)aMino]-7-Methoxy-6-quinazolinyl]oxy]-N-hydroxyheptanaMide;7-[[4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yl]oxy]-N-hydroxyheptanamide CUDC-101;7-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide;CUDC-101, >=98% |
CAS: | 1012054-59-9 |
MF: | C24H26N4O4 |
MW: | 434.48764 |
EINECS: | -0 |
Product Categories: | Inhibitor;Antineoplastic;Inhibitors |
Mol File: | 1012054-59-9.mol |
CUDC-101 Chemical Properties |
Melting point | 174-177℃ |
density | 1.28 |
storage temp. | -20°C |
CUDC-101 Usage And Synthesis |
Usage | Inhibitor of HDAC, EGFR, and HER2 with an IC50 of 4.4, 2.4, and 15.7 nM, respectively. |
Usage | CUDC-101 is a potent multi-acting HDAC (histone deacetylase), EGFR (epidermal growth factor receptor), and HER2 ( human epidermal growth factor receptor 2) inhibitor for the treatment of cancer. |
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