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CAS NO.10118-90-8
| Minocycline Basic information |
| Product Name: | Minocycline |
| Synonyms: | 12,12a-tetrahydroxy-1,11-dioxo--10;2-naphthacenecarboxamide,4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro;-3,10,12,12a-tetrahydroxy-1,11,-dioxo-,(4s-(4alpha,4aalpha,5aalpha,12aalpha));7-dimethylamino-6-demethyl-6-deoxytetracycline;cl59806;minocyclin;7-DIMETHYLAMINO-6-DEMETHYL-6-DEOXYTETRACYCLINE HYDROCHLORIDE;7-DIMETHYLAMINO-6-DEMETHYL-6-DEOXYTETRACYCLINE, HCL |
| CAS: | 10118-90-8 |
| MF: | C23H27N3O7 |
| MW: | 457.48 |
| EINECS: | 237-099-7 |
| Product Categories: | |
| Mol File: | 10118-90-8.mol |
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| Minocycline Chemical Properties |
| CAS DataBase Reference | 10118-90-8(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Naphthacenecarboxamide, 4,7-bis(dimethylamino)-1,4, 4a,5,5a,6,11,12a-octahydro- 3,10,12,12a-tetrahydroxy- 1,11-dioxo-, (4S,4aS,5aR,12aS)-(10118-90-8) |
| Safety Information |
| Hazardous Substances Data | 10118-90-8(Hazardous Substances Data) |
| Minocycline Usage And Synthesis |
| Usage | Minocycline is a semi-synthetic tetracycline prepared by sequential hydrogenolysis, nitration and reductive methylation. Minocycline, together with doxycycline, is regarded as a ‘third generation’ tetracycline largely replacing the natural products and pro-drugs produced in the early 1950s for mainstream antibiotic applications. Like all tetracyclines, minocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis. Minocycline has been extensively cited in the literature with over 5,000 references. |
| Minocycline Preparation Products And Raw materials |
| Preparation Products | [4S-(4alpha,4aalpha,5aalpha,12aalpha)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxonaphthacene-2-carboxamide monohydrochloride |
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